Pii: S0925-4773(01)00585-8

Vsx1, a rapidly evolving paired-like homeobox gene expressed in cone bipolar cells

The paired-like homeodomain (HD) protein Chx10 is distinguished by the presence of the CVC domain, a conserved 56 amino acid sequence C-terminal to the HD. In mammals, Chx10 is essential both for the proliferation of retinal progenitor cells and for the formation or survival of retinal bipolar interneurons. We describe the cloning and characterization of a mouse Chx10 homologue, Vsx1; phylogene...

14th INTERNATIONAL CONGRESS of DEVELOPMENTAL BIOLOGY

Subject index to Special Review Section

Pbx4, a new Pbx family member on mouse chromosome 8, is expressed during spermatogenesis

Members of the Pbx family are involved in a diverse range of developmental processes including axial patterning and organogenesis. Pbx functions are in part mediated by the interaction of Pbx proteins with members of the Hox and Meis/Prep families. We have identified a fourth mammalian Pbx family member. Pbx4 in the mouse and PBX4 in humans are located on chromosome 8 and chromosome 19, respect...

Drosophila windpipe codes for a leucine-rich repeat protein expressed in the developing trachea

The embryonic tracheal system of Drosophila provides an important model for understanding the process of epithelial branching morphogenesis. Here we report the sequence and expression analysis of a novel tracheal gene, named windpipe (wdp). wdp is identical to the predicted gene CG3413 and encodes a transmembrane, leucine-rich repeat family member. wdp transcripts appear abruptly at stage 15 an...